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There are no restrictions on food, beverages, or activities while taking Nexium, unless otherwise directed by your doctor. What should my health care professional know before I take Esomeprazole? Esomeprazole provides improved acid control in patients with gastroesophageal reflux disease. Nexium capsules should be applied one hour before a meal. Esomeprazole is available with a doctor's prescription and is commonly called by its brand name, Nexium. If you buy any medicines check with a pharmacist that they are safe to take with Esomeprazole. Because Nexium is likely to appear in breast milk you will need to take Nexium. Nexium is the newer formulation of the original Omeprazole product - both prescription drugs used to treat ulcers, gastroesophageal reflux disease. What should my health care professional know before I take Esomeprazole?