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Your family or other caregivers should also be alert to changes in your mood or symptoms. You stop taking Paroxetine. Depression after nearly ten years and over ten million patient treatments. Recent studies suggest an increased risk of Paxil birth defects for pregnant women during their first trimester. Social anxiety disorder and generalized anxiety disorder. Research has shown that depression and anxiety disorders usually require long-term treatment because of their chronic nature and the risk of relapse. Studies have shown Paxil is an excellent treatment for people in this age group - where chronic depression can affect a large proportion of this population. Alcohol, which can increase some of the side effects of Paroxetine. Depression and anxiety disorders usually require long-term treatment because of their chronic nature and the risk of relapse.