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You must wait at least 14 days before you start taking an MAO inhibitor before you can take Celexa. Celexa is the newest antidepressant to be approved by theFDA. Citalopram is an antidepressant in a group of drugs called selective serotonin reuptake inhibitors. Celexa helps to restore the brain's chemical balance by increasing the supply of a chemical messenger in the brain. Celexa insomnia may be a side effect from this drug prolonging serotonin's action within the brain. In Celexa insomnia. It may take several weeks of treatment before maximum effects are seen. Do not stop using Celexa without first talking to your doctor. Depression, Celexa extends the length of time serotonin remains active in the brain called serotonin.