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If Valtrex prevents the spread of the herpes virus. Valtrex can greatly decrease the length of time you experience an outbreak and may possibly reduce the number of incidences. Some of the most common adverse reactions to the drug are headache, nausea, diarrhea, and vomiting. It more than 24 hours after the start of signs or symptoms. Valaciclovir is a drug, an esterified version of aciclovir that has greater oral bioavailability than aciclovir. It can be a great treatment option for you because it can help reduce the number of your genital herpes outbreaks. Probably the most common adverse reactions to the drug are headache, nausea, diarrhea, and vomiting. To them for the rest of their life.