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Use of Esomeprazole in pregnant women has not been appraised. Nexium is the newer formulation of the original Omeprazole product - both prescription drugs used to treat the symptoms of GERD and other conditions involving excessive stomach. Nexium decreases the amount of acid produced in the stomach and intestines by blocking the enzyme in the wall of the stomach that produces acid. What should you watch for while taking Esomeprazole? Esomeprazole works best if taken on an empty stomach at least one hour before a meal. Nexium decreases the amount of acid backing up into the esophagus and causing reflux symptoms.
