Levaquin is a quinolone antibiotic used to treat severe and life threatening bacterial infections. Levaquin can increase the effects of the anticoagulant warfarin. Levofloxacin is rapidly and essentially completely absorbed after oral administration. Some medications will cause health effects and serious reactions when taken with Levaquin. If you have any questions. Medications that have been introduced within this class is known as the fluoroquinolone antibiotic, which is in a group of medications used generally to treat difficult infections, most commonly those that affect the urinary tract in patients.