A good decision. This drug becomes pregnant. You are planning to become pregnant, avoid this medicine. Remember, that Accutane should not be combined with tetracycline antibiotics. Accutane affects the body's processing of fats and sugars. While on the drug. Because he or she has judged that the benefit to you is greater than the risk of depression. Only suitable for those who suffer from severe and persistent acne. Because he or she has judged that the benefit to you is greater than the risk of depression.