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Like any antidepressant, not everyone responds or tolerates any given medication. Do not take Celexa together with a monoamine oxidase inhibitor. You may have thoughts about suicide when you first start taking an MAO inhibitor before you can take Celexa. It may take several weeks of treatment before maximum effects are seen. Celexa is an antidepressant medication that affects neurotransmitters, the chemical transmitters within the brain. Celexa is an antidepressant drug used to treat the symptoms of depression but can also be prescribed for social anxiety disorder, panic disorder or obsessive-compulsive disorder.