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Aldactone usually is taken once a day in the morning with breakfast or twice a day with breakfast and lunch. Aldactone can also be used in combination with other medicines to treat precocious puberty or myasthenia gravis. You needing to get up in the night to visit the toilet. As a tablet to take by mouth. There is excess production of Aldosterone by the adrenal glands. As water tablets. As a tablet to take by mouth.